glycoengineering

SUMMARY

What it does

This Agent Skill provides capabilities for analyzing and engineering protein glycosylation. It includes functions to scan protein sequences for canonical N-glycosylation sequons (N-X-S/T, where X is not Proline), predict O-glycosylation hotspots using a heuristic based on local Ser/Thr density, and mutate sequences to eliminate or introduce glycosylation sites. The skill also references external glycoengineering tools and databases, such as NetOGlyc 4.0, GlycoShield-MD, GlycoWorkbench, GlyConnect, and UniCarbKB, with usage examples. The skill content is derived from a single SKILL.md file (12480 bytes) that was fetched and inspected; no runtime behavior or tool execution was observed.